Alka-Seltzer extra strong contains caffeine along with Aspirin, Sodium Hydrogen Carbonate, Citric Acid. These are very quick acting non-steroidal anti-inflammatory drugs (NSAIDS), used for the treatment of pain and reduction. It is useful in pains such as headache, , backache, period pain, toothache, migraine and sore throat, etc. Doctors also recommend the drug for swelling and stiffness, strains and sprains. People who have severe kidney or liver problems, severe heart problems or who are pregnant or breast-feeding should take the drug after consulting with doctor. The drug should be taken after consulting with doctor if in children under 16 years. To use the product it must be dissolved in water before use.